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Skin Science Hero

Cutting-edge science designed around the biology of skin aging

Aging is a biological process, not just a cosmetic concern. We design our prescription formulations to target the biological pathways associated with skin aging to support both how skin looks and how it functions over time.

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Subject to medical consultation.
Skin Science Hero

Cutting-edge science designed around the biology of skin aging

Aging is a biological process, not just a cosmetic concern. We design our prescription formulations to target the biological pathways associated with skin aging to support both how skin looks and how it functions over time.

Get started
Subject to medical consultation.

Treat the visible signs of aging at the biological core

Agency is designed as a system of personalized treatments that work together across these pathways. Each product specializes in a primary area while supporting multiple mechanisms associated with skin aging.

Inflammation

Inflammation

As we age, low-grade inflammation can persist in the skin, accelerating the breakdown of collagen and elastin while impairing the skin's ability to repair itself. This chronic inflammation, often called inflammaging, is associated with wrinkles, loss of firmness, and increased skin sensitivity.

Oxidative stress

Oxidative stress

UV rays, pollution, stress, and other environmental aggressors generate unstable molecules called free radicals. Over time, these molecules damage proteins, lipids, and skin cells, contributing to dullness, uneven tone, discoloration, and premature aging.

Protein degradation

Protein degradation

UV rays, pollution, stress, and other environmental aggressors generate unstable molecules called free radicals. Over time, these molecules damage proteins, lipids, and skin cells, contributing to dullness, uneven tone, discoloration, and premature aging.

Cellular repair

Cellular repair

Healthy skin relies on continuous repair and renewal. Over time, aging cells become less efficient at clearing damage and maintaining healthy function. As repair processes slow, skin can become less resilient, slower to recover, and more vulnerable to visible aging.

DNA damage

DNA damage

Every day, skin is exposed to factors that can damage cellular DNA. As repair mechanisms become less efficient with age, damage accumulates and can disrupt normal skin function, contributing to visible signs of aging and slower recovery over time.

Inflammation

As we age, low-grade inflammation can persist in the skin, accelerating the breakdown of collagen and elastin while impairing the skin's ability to repair itself. This chronic inflammation, often called inflammaging, is associated with wrinkles, loss of firmness, and increased skin sensitivity.

Our breakthrough formulas






Shop all skincare

Chosen for evidence.

Designed for results.

We combine clinically proven active ingredients to target multiple biological pathways associated with skin aging.

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Subject to medical consultation.
Tretinoin

Rapamycin

Targets cellular aging pathways for visibly rejuvenated skin

Resveratol

Resveratrol

Protects against oxidative damage and supports skin renewal

Estriol

Estriol

Restores skin firmness and hydration lost to hormonal aging

Tretinoin 2

Tretinoin

Helps reduce fine lines and unwanted dark spots, plus improves skin texture

Hydroquinone

Hydroquinone

The gold-standard prescription ingredient for fading dark spots and evening skin tone

Rapamycin

Targets cellular aging pathways for visibly rejuvenated skin

Dr. Whitney

Dr. Whitney Tolpinrud, MD, FAAD

Board-Certified Dermatologist and Agency Medical Director

Dr. Whitney leads the clinical strategy behind every Agency treatment—from the prescriptions your provider recommends to the evidence-based regimens that guide your care. She and her medical team make sure every patient gets personalized, dermatologist-backed treatment that actually works.

Dr. Whitney

Dr. Whitney Tolpinrud, MD, FAAD

Board-Certified Dermatologist and Agency Medical Director

Dr. Whitney leads the clinical strategy behind every Agency treatment—from the prescriptions your provider recommends to the evidence-based regimens that guide your care. She and her medical team make sure every patient gets personalized, dermatologist-backed treatment that actually works.

Dr. Felipe Jimenez, PhD

Head of Innovation at Agency


Dr. Felipe is the scientist behind the formulas—leading product development, formulation chemistry, and clinical testing of all Agency products. He is responsible for technical aspects of manufacturing and quality and also oversees Agency's intellectual property portfolio.

Dr. Felipe Jimenez
Dr. Felipe Jimenez

Dr. Felipe Jimenez, PhD

Head of Innovation at Agency


Dr. Felipe is the scientist behind the formulas—leading product development, formulation chemistry, and clinical testing of all Agency products. He is responsible for technical aspects of manufacturing and quality and also oversees Agency's intellectual property portfolio.

Questions?






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Subject to medical consultation.